The Efficacy of Obstructive Sleep Apnea Surgery on Mean Platelet Volume, Neutrophil/Lymphocyte, and Platelet/Lymphocyte Ratios

Objective: Obstructive sleep apnea syndrome (OSAS) is a common sleep disorder characterized by repeated upper airway collapse. As types of surgical modalities have been defned according to the level of airway obstruction, uvulopalatal fap and anterior palatoplasty are 2 of the main surgical options for patients with collapse in the soft palate and oropharynx region. The aim of our study is to show the efect of surgery on neutrophil–lymphocyte ratio, platelet–lymphocyte ratio, and mean platelet volume values in OSAS patients.

Methods: The medical records of 125 patients with OSAS diagnosis in between January 2012 and December 2014 were evaluated retrospectively. Age, gender, body mass index, polysomnography results, Epworth Sleepiness scale (ESS), complete blood count values, and surgical results of the patients were evaluated.

Results: A statistically signifcant decrease was observed in the mean apnea–hypopnea index, oxygen desaturation index, and ESS scores in the postoperative period (P < .001). Considering all patients, a statistically signifcant decrease was observed in th mean platelet volume (MPV) values in the postoperative period (P < .001) and no statistically signifcant change was observed in the mean neutrophil–lymphocyte ratio (NLR) and platelet–lymphocyte ratio (PLR) values (P = .808 and P = .117). In patients whose anterior palatoplasty (78 patients) results were considered successful, a statistically signifcant decrease was observed in MPV and PLR values (P < .001 and P = .038), while no signifcant change was observed in NLR values (P = .185). In those with successful uvulopalatal fap (47 patients) results, a statistically signifcant decrease was observed in MPV values (P < .001), while no signifcant change was observed in NLR and PLR values (P=.809 and P=.154).

Conclusion: While it was observed that MPV values were associated with OSAS, no clear relationship was found between NLR and PLR values.

Cite this article as: Altan E, Yucel V, Saylam G, Bayir O. The efcacy of obstructive sleep apnea surgery on mean platelet volume, neutrophil/lymphocyte, and platelet/lymphocyte ratios. Eur J Rhinol Allergy 2024;7(2):42-49.